By 1803, a number of members of "The Religious Society of Friends," commonly called "Quakers," arrived from New England to settle a few miles north of Canandaigua in the small community of Farmington N.Y., where they organized a "Monthly Meeting." The following year, some of the Farmington Quakers moved to land just west of the Genesee River in the present Town of Wheatland, Monroe County. They were soon joined by other Quaker families from Chenango County in central New York. The "Wheatland Meeting" was organized and, in 1825, a small frame meeting house was put up. A cobblestone meeting house followed in 1834.

The Wheatland Quakers did not always dwell in perfect harmony with one another in regard to the interpretation of their beliefs. In 1854, after years of doctrinal differences, the Orthodox Quakers split away from the "Hicksites," a less fundamental group. The Hicksites stayed on in the cobblestone meeting house, while the orthodox group erected a plain, one-story meeting house a few miles away. That meeting house now stands in a quiet setting at the museum, away from the busier part of town.

Some buildings are simple in the extreme. The interior of the meeting house (which has separate entrances for men and women) was divided by partitions that could be opened or closed, depending upon whether the men or women were to meet separately or together. The hard wooden benches have been reproduced from surviving examples of originals. Facing the seated congregation is a stepped platform across the front of the meeting house, where the older Friends sat. Two stoves, two wood boxes and two sets of shelves for books completed the interior arrangement.

The meeting was "laid down" (to use the Quaker term) in 1873, when the size of the congregation dwindled, and the structure was converted to farm use. In 1967, it was conveyed to the museum by Mrs. Richard Field, a descendant of one of the first Wheatland Friends.