Beginning early in the 19th Century, private (sometimes referred to as "select") schools for girls were established in many western New York State villages and towns, as well as in the cities. This was, in part, to give the girls educational opportunities equal to those offered at the boys' private academies, and in part because of the concern of church groups to provide what they considered appropriate instruction for young ladies.

The Romulus Female Seminary was built in 1855. According to town records, a subscription of some $85 was collected to buy a bell for the seminary then being built, with said bell to be hung in its tower.

The Seminary closed in 1883, and the Presbyterian Church of Romulus purchased it to use as a chapel. It was moved to a site alongside the church.

In 1970, the old seminary building was moved once more, this time to Genesee Country Village. It has been restored and furnished as a typical girls' small seminary of the period. The well-appointed classroom contains a piano, drawing table, blackboard, wood stove, plenty of light and of course, a well-qualified teacher.

Built toward the end of the Greek Revival period, the one-story building includes the basic elements of that style. Two square columns are topped by a wide entablature which, in turn, is capped with a pediment with full returns of the cornice. The iron cresting on the bell tower is of a later period, presumably added when the seminary was converted into a chapel.